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ترجمه مقاله DNA و ژنوم

نویسنده :سودا ب
تاریخ:دوشنبه 28 اردیبهشت 1394-10:44 ق.ظ

عنوان انگلیسی مقاله: DNA and Genome
عنوان فارسی مقاله: DNA و ژنوم.
دسته: پزشکی
فرمت فایل ترجمه شده: WORD (قابل ویرایش)
تعداد صفحات فایل ترجمه شده: 9
ترجمه ی سلیس و روان مقاله آماده ی خرید می باشد.
_______________________________________
چکیده ترجمه:
اندازه ژنوم ها، در صورتی که با ژنوم های دیگر ترکیب گردد، یا DNA هایی را از طریق یک ویروس یا مکانیسم های دیگر انتقال افقی گرداوری کند، ممکن است به سرعت تغییر کند. دسترسی به DNA جدید به معنی دسترسی به ژن جدید می باشد اما ژنوم ها دارای محدودیت اندازه می باشند. چرا؟ هر چرخه رونوشت، برای ژنوم های بزرگتر هزینه ای را در بر دارد و بنابراین ژنوم ها می بایست تعادلی را برای مقدار رونوشت DNA با داشتن ژن هایی که دارای مزایای گزینشی تحت شرایط خاص می باشند، ایجاد کنند. برعکس از دست دادن DNA و ژن ها می تواند مفید باشد اگر سلول های مربوطه شکاف های جدید ( همانند گونه های دگیر) را پر کنند. اگر ژن ها، دیگر مفید نباشند، DNA ها ار بین رفته و ژنوم های کارآمدتر مزایای گزینشی را خواهند داشت. از آنچه که تا به حال بیان کرده ایم  اندازه ژنوم ها برای گروهی از گونه ها در یک اندازه نسبتا محدودی قرار می گیرند. برای نمونه بخش های K وo بدن فرد، DNA جدیدی را کسب می کنند اما باکتری های مربوط به روده دارای ژنوم هایی در محدوده 4 و 5 MB می باشند. زمانی که آن ها DNA جدیدی را کسب می کنند، سلول ها به تعادل حیاتی ژتوم ، با اندازه بهینه شده و ژن ها شمارش شده بر می گردند.
شما ممکن است این موضوع را در ذهن داشته باشید که 200 توالی ژنوم کافی بوده و نیاز به توالی بیشتر نمی باشد اما در تعداد ژنوم های نسبی، قدرتی وجود دارد. تصور کنید که تمام عمر خود را در یک غار زندگی کرده اید و روزی که بیرون آمدید یک پرنده امربکای شمالی آبی رنگ و یک زاغ آبی رنگ را دیده اید، بر این اساس شما ممکن است تصور کنید که تمام پرندگان آبی رنگ هستند. در روزهای بعد شما یک سهره قرمز رنگ و یک قناری زردرنگی را می بینید و شما ممکن است به این نتیجه گیری برسید که تمام پرندگان از همان ابتدای وجودشان دارای رنگ های خاصی می باشند. استفاده از نمونه های کمتر ممکن است شما را منتهی به نتیجه گیری اشتباهی بکند. زمانی که شما مرغ مگس خوار، شترمرغ و پنگوئن را مشاهده می کنید این موارد باعث تعجب شما می شود. زمانی که ما در ارتباط با تنوع پرندگان مطالعات بیشتری را انجام می دهیم، چیزهای بیشتری نیز در ارتباط با آن ها یاد می گیریم. و زمانی که ما نمونه های بیشتری در دست داریم، چیزهای بیشتری نیز در ارتباط با ژنوم ها یاد می گیریم. به هر حال منابع محدود بوده و بنابراین می بایست به طور آگاهانه ای انتخاب کنیم که چه ژنومی را می خواهیم انتخاب کنیم تا بتوانیم توانایی های خود را در ارتباط با فرا گرفن آن ها افزایش دهیم.

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